“The lack of vital nutrients to the brain produced a signal to “downsize” the neuronal population to ensure the survival of the most essential.”
Hello, this is Dr Dennis again. It’s so lovely to “see” you here. I hope you are enjoying all these reading and educational materials I have prepared for you and your family. Let’s do this together!
Today, we continue exploring all the different subtypes of Alzheimer’s. I hope you are not lost thus far! If you have any questions, please email info@primegardensrs.com.au, and our staff will forward your query to me.
This subtype is characterised by a “loss of neuronal volumes.” This is due to deficiencies in vital hormonal support, such as thyroid, estrogen, testosterone, pregnenolone, adrenal gland hormones, Brain-derived growth factor (BDNF), and Vitamin D.
The characteristic clinical presentation of this subgroup is usually people in their 80s who are “not interested” in their surroundings. They have severe impairment in retaining information but no issues with organising, dressing, or language (these are affected in type 1).
The Potential Solutions
- Replace and optimise support with vitamin D, B, BDNF, and Nerve growth factor (NGF), e.g.1. ALCAR—Acetyl-L-Carnitine. This nutrient plays a crucial role in energy production in the mitochondria, your cells’ power plants.
- Hericium – Lion’s mane, an editable mushroom with many medicinal benefits, including neuroprotection, “leaky gut caused by Inflammatory bowel disease.”
- Quercetin – Quercetin is a flavanol (a type of pigment). Quercetin has antioxidantproperties that help protect cells against oxidative damage. Food and drinks that contain Quercetin are Broccoli, Capers, Onions, Apples, Wine, Tea, and Nuts.
- Whole Coffee Fruit Concentrate (WCF). It is a natural supplement derived from the coffee plant. It is a rich source of antioxidants, vitamins, minerals, and other beneficial compounds.
- Synaptogenesis (formation of new synapses/connections between neurons). Citicoline—Citicoline is crucial in forming neuron cell membranes in the human body. A 2022 review of more than 800 studies on citicoline concluded that it improves memory and attention in generally healthy people and people with vascular dementia. Many foods contain Citicoline, vegetables like broccoli and cauliflower, fishlike salmon, poultry like chicken breast, etc.
- Secretagogues – a type of insulin-releasing medicine (Secretagogues) that stimulates the beta cells to make more insulin.
- Maintain a healthy weight – a suboptimal weight will reduce our body’s ability to produce hormones.
- Adequate amount of Cholesterol – sex hormone (estrogen & testosterone) requires cholesterol.
What are the main take-home messages?
- Subtype 2 of Alzheimer’s(“cold”) is characterised by deficiencies of many critical nutrients, hormones and minerals that lead to “retraction” of the neuronal network.
- The “retraction” aimed to protect the essential neuronal network at the expense of short-term memory, which is vital in retaining new information.
- The solution is to replace the deficit, not to remove the Amyloid, which is purely a messenger forcibly. The rest will fall into place!
- Stress management.
- Reasonable and adequate amounts of good fat and cholesterol will ensure healthy levels of hormones like testosterone.